One of the questions I have is how will this effect the price of prescription medicines.  While I do not know the origin of this comment I saw the following in a forum I follow:

Health advocates and generic drug-makers sounded that alarm over a leaked TPP draft that showed greater protection for pharmaceutical companies, a U.S. demand. The U.S. has also pushed for longer exclusivity for cutting-edge biologics treatments — seeking 12 years, compared to zero currently guaranteed in some developing countries. But sources say the final deal will probably include something similar to the eight-year exclusivity period already in the Canada-EU deal. Published reports also suggest the U.S. has pared down some of the early positions in the leaked text.